Publications

1993 - Joad, J.P. , K.E. Pinkerton, and J.M. Bric. Effects of sidestream smoke exposure and age on pulmonary function and airway reactivity in developing rats. Pediatric Pulmonology 16:2281-288.

1994 - Rajini, P; Last, JA; Pinkerton, KE; Hendrickx, AG; Witschi, H. Decreased fetal weights in rats exposed to sidestream cigarette smoke. Fundamental and Applied Toxicology 22:400-404.

1994 - Teague, S.V. ,K.E. Pinkerton, M. Goldsmith, A Gebremichael, S. Chang, R.A.Jenkins and J.H. Moneyhun. Sidestream cigarette smoke generation and exposure system for environmental tobacco smoke studies. Inhalation Toxicology 6:79-93.

1994 - Rajini, P. , J.A. Last, K.E. Pinkerton, A.G. Hendrickx and H. Witschi. Decreased fetal weights in rats exposed to sidestream cigarette smoke. Fundamental and Applied Toxicology 22:400-404.

1995 - Witschi, H; Lundgaard, SM; Rajini, P; Hendrickx, AG; Last, JA. Effects of exposure to nicotine and to sidestream smoke on pregnancy outcome in rats. Toxicology Letters 71:279-86.

1995 - Witschi, H; Espiritu, I; Maronpot, RR; Pinkerton, KE; Jones, AD. The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis 18:2035-42.

1995 - Witschi, H. , K.E. Pinkerton, C.R.E. Coggins, A. Penn and G.B. Gori. Environmental tobacco smoke: experimental facts and societal issues. Fundamental and Applied Toxicology 24:3-12.

1995 - Joad, J.P. , C. Ji, K.S. Kott, J.M. Bric and K.E. Pinkerton. In utero and postnatal effects of sidestream cigarette smoke exposure on lung function, hyperresponsiveness, and neuroendocrine cells in rats. Toxicology and Applied Pharmacology 132:63-71.

1995 - Gebremichael, A. , A.M.Chang, A.R. Buckpitt, C.G. Plopper and K.E. Pinkerton. Postnatal development of cytochrome p4501A1 and 2B1 in rat lung and liver: effect of aged and diluted sidestream cigarette smoke. Toxicology and Applied Pharmacology 135:246-253.

1996 - Witschi, H. , V.I.C. Oreffo and K.E. Pinkerton. Six-month exposure of strain A/J mice to cigarette sidestream smoke: cell kinetics and lung tumor data. Fundamental and Applied Toxicology 26:32-40.

1996 - Gebremichael, A. , K. Tullis, M.S. Denison, J.M. Cheek, and K.E. Pinkerton. Ah-Receptor-Dependent Modulation of Gene Expression by Aged and Diluted Sidestream Cigarette Smoke. Toxicology and Applied Pharmacology 141:76-83.

1996 - Roberts, K.A. , A.A. Rezai, K.E. Pinkerton, and J.C. Rutledge. Effect of environmental tobacco smoke on LDL accumulation in the artery wall. Circulation 94:2248-2253.

1996 - Joad, J.P. , K.P. Avadhanam, K.C. Watt, K.S. Kott, J.M. Bric, and K.E. Pinkerton. Effects of extended sidestream smoke exposure on components of the C-fiber axon reflex. Toxicology 112:195-203.

1996 - Gospe, S.M. , S.S. Zhou, and K.E. Pinkerton. Effects of environmental tobacco smoke exposure in utero and/or postnatally on brain development. Pediatric Research 39:494-498

1996 - Pinkerton, K.E. ,J.L. Peake, I. Espiritu, M. Goldsmith, and H.P. Witschi. Quantitative histology and cytochrome P450 immunocytochemistry of the lung parenchyma following six months exposure of strain A/J mice to cigarette sidestream smoke . Inhalation Toxicology 8:927-945.

1997 - Witschi, H. Tobacco smoke as a mouse lung carcinogen. Experimental Lung Research 24:385-394.

1997 - Seymour, BW; Pinkerton, KE; Friebertshauser, KE; Coffman, RL; Gershwin, LJ. Second-hand smoke is an adjuvant for T helper-2 responses in a murine model of allergy. Journal of Immunology, 159:6169-75.

1997 - Witschi, H. , I. Espiritu, R.R. Maronpot, K.E. Pinkerton and A.D. Jones. The carcinogenic potential of the gas phase of environmental tobacco smoke. Carcinogenesis 18(11):2035-2042.

1997- Witschi, H. ,I. Espiritu, J.L. Peake, K. Wu, R.R. Maronpot, and K.E. Pinkerton. The carcinogenicity of environmental tobacco smoke. Carcinogenesis 18:575-586.

1997 - Witschi, H. , J.P. Joad, and K.E. Pinkerton. The toxicology of environmental tobacco smoke. Annual Review of Pharmacology and Toxicology 37:29-52.

1998 - Witschi, H; Espiritu, I; Yu, M; Willits, NH. The effects of phenethyl isothiocyanate, N-acetylcysteine and green tea on tobacco smoke-induced lung tumors in strain A/J mice. Carcinogenesis 19:1789-1794.

1998 - Ji, C.M. , F.H. Royce, U. Truong, C.G. Plopper, G. Singh and K.E. Pinkerton. Maternal exposure to environmental tobacco smoke alters Clara cell secretory protein expression in fetal rat lung. American Journal of Physiology 275 (Lung Cellular and Molecular Physiology) 19:L870-876.

1999 - Izzotti A. , BagnascoM. , D'Agostini F. , Cartiglia C. , Lubet R.A. , Kelloff G.J. and De Flora S. : Formation and persistence of nucleotide alterations in rats exposed whole-body to environmental cigarette smoke. Carcinogenesis, 20, 1499-1505,

1999 - Joad, J.P. , J.M. Bric, J.L. Peake, and K.E. Pinkerton. Perinatal exposue to aged and diluted sidestream cigarette smoke procedures airway hyperresponsiveness in older rats. Toxicology and Applied Pharmacology, 155:253-260.

2000 - D'Agostini F. , Balansky R. , Pesce C.M. , Fiallo P. , Lubet R.A. , Kelloff G.J. and De Flora S. : Alopecia and hair follicle cell apoptosis in mice exposed to environmental cigarette smoke. Toxicol. Lett. , 114, 117-123.

2000 - Witschi, H; Uyeminami, D; Moran, D; Espiritu, I. Chemoprevention of tobacco-smoke lung carcinogenesis in mice after cessation of smoke exposure. Carcinogenesis, 21:977-82.

2000 - Lee, C.Z. , F.H. Royce, M.S. Denison, and K.E. Pinkerton. Effect of in utero and postnatal exposure to environmental tobacco smoke on the developmental expression of pulmonary cytochrome P450 monooxygenases. Journal of Biochemical and Molecular Toxicology 14:121-130.

2000 - Balansky R.M. , D'Agostini F. , Izzotti A. and De Flora S. : Less than additive interaction between cigarette smoke and chromium(VI) in inducing clastogenic damage in rodents. Carcinogenesis, 21, 1677-1682,.

Izzotti A. , Balansky R.M. ,D'Agostini F. , Bennicelli C. , Myers S.R. , Grubbs C.J. , Lubet R.A. , Kelloff G.J. and De Flora S. : Modulation of biomarkers by chemopreventive agents in smoke-exposed rats. Submitted for publication.

D'Agostini F. , Balansky R.M. , Bennicelli C. , Lubet R.A. , Kelloff G.J. and De Flora S. : Pilot studies evaluating the lung tumor yield in cigarette smoke-exposed mice. Submitted for publication.

Izzotti A. , Camoirano A. , Cartiglia C. , Tampa E. and De Flora S. : Formation of DNA adducts in the aorta of smoke-exposed rats. Modulation by five chemopreventive agents. Submitted for publication.

2001 - M. Aufderheide, D. Ritter, J.W. Knebel, and G. Scherer : A method for in vitro analysis of the biological activity of complex mixtures such as sidestream cigarette smoke. Exp Toxic Pathol 2001; 53: 141-152 Urban & Ficher; http:/www.urbanfischer.de/journals/exptopath.